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Dr. Mandip Sachdeva is currently a Professor and Section leader, Pharmaceutics at College of Pharmacy at Florida A & M University (FAMU), Tallahassee, Florida. Over his career, Mandip has delivered more than 250 plenaries, keynote and invited talks in international events and meetings and produced more than 190 original publications.His research interests include cancer drug delivery, 3D-printing of tumor cells, and formulating and developing targeted nanoparticles, exosomes and cannabinoids for cancer treatments.

During our conversation, Mandip previews his CannMed 26 oral presentation titled, “Cannabigerol Potentiates Chemotherapy through Multi-Modal Tumor Suppression in Pancreatic Cancer“, which includes insights into his research on using cannabinoids (particularly CBG) to treat pancreatic cancer—one of the most difficult cancers to treat. We cover:

The process Mandip’s team used to determine CBG had the best anti-cancer effects against pancreatic cancer
CBG’s mechanism of action, which targets multiple pathways related to immune regulation, cell death, and tumor migration control
Why cannabinoids are best used as adjuncts to chemotherapy and not as a standalone treatment
Higher doses of CBG (up to 100 mg/kg) were non-toxic and further extended survival when combined with reduced chemo doses
Future research directions, including new combinations of cannabinoids and chemotherapy as well as new formulations for better absorption and bioavailability

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