We report the presence of Endotoxin in high and low CFU/g cannabis flower samples. In some jurisdictions, cannabis samples over 100,000 CFU/g of total aerobic count, are prioritized for decontamination using ozone, E-beam, X-ray or gamma ray exposure. While these methods are well known for reducing viable colony forming units, they are less effective at removing the DNA or endotoxin. Less is known about the residual endotoxin levels that might exist on such decontaminated products. To estimate this, we evaluated endotoxin levels of hemp samples in Massachusetts that are not subject to microbial testing and compared those to store-bought cannabis flower that must pass 100,000 CFU/g limits in Total Aerobic Count testing. We find significant levels (over 500EU/g) of endotoxin on all pre-rolls tested, regardless of CFU/g microbial testing requirements. Endotoxins on inhaled products can trigger asthmatic attacks. In light of a recent asthmatic fatality in a Massachusetts pre-roll facility, further scrutiny of decontamination procedures and their resulting endotoxin levels is required.