9:00 am - 9:05 am - Welcome and Introductions: Bonni Goldstein, Dustin Sulak, and Ethan Russo

9:05 am - 9:45 am - Clinical Endocannabinoid Deficiency (CED) Revisited: Ethan Russo
This presentation will examine the evidence that migraine, fibromyalgia, irritable bowel syndrome, major depression, post-traumatic stress and other conditions are related to deficiencies in endocannabinoid tone, along with their implications for therapeutic management.

9:45 am - 10:25 am - Foundational Concepts of Cannabis as Medicine: Dustin Sulak

10:25 am - 10:35 am - Break

10:35 am - 11:15 am - Beyond THC and CBD: Minor Cannabinoids: Bonni Goldstein
This session will explore emerging research on lesser-known cannabinoids beyond THC and CBD, such as CBG, CBDA, and CBN. Clinicians will gain insight into their pharmacology, potential therapeutic applications, and the evolving clinical evidence supporting their use in pain management, inflammation, anxiety, nausea, and sleep disorders.

11:15 am - 12:00 pm - Chronic Pain: Clinical Strategies for Success in Challenging Cases: Dustin Sulak
Chronic pain is one of the most common indications for which people use cannabis. This presentation will review the clinical evidence supporting the use of cannabis for chronic pain and its role in opioid reduction, and provide practical approaches to challenging cases and etiologies of pain.

12:00 pm - 1:45 pm - Lunch

1:45 pm - 2:30 pm - Cannabinoids and the Immune System: Therapeutic Approaches to Autoimmune Disorders: Bonni Goldstein
This presentation examines the immunomodulatory effects of cannabinoids and their potential role in managing autoimmune diseases. Clinicians will review current evidence on how the endocannabinoid system influences immune regulation, inflammation, and cellular signaling, with discussion of clinical applications in conditions such as inflammatory bowel disease and multiple sclerosis. Practical considerations for integrating cannabinoid-based therapies into patient care will also be addressed.

2:30 pm - 3:15 pm- Neurology with Focus on Alzheimer disease and ALS: Ethan Russo
This presentation will examine the pathophysiology of these degenerative conditions, their relationship to the endocannabinoid system and the various mechanisms by which cannabis-based medicine may address the underlying pathology and associated symptoms.

3:15pm - 3:25 pm - Break

3:25 pm - 4:05 pm - Cannabinoids in Sports and Recovery: Emerging Science and Clinical Applications: Bonni Goldstein
There is a growing body of research on cannabinoids in athletic performance, recovery, and injury management. Clinicians will learn how cannabinoids influence pain modulation, inflammation, sleep, and neuroprotection, as well as their potential role in enhancing recovery and reducing reliance on opioids and NSAIDs. The discussion will also address product selection, and evidence-based guidance for advising athletes and active patients.

4:05 pm - 4:45 pm – Cannabis in Pregnancy and Lactation: Current Evidence: Dustin Sulak
How do you counsel pregnant and lactating patients regarding the risks of using cannabis? How much THC is delivered to the nursing infant and what are the consequences? Is it ethical and effective to treat pregnant and lactating mothers with cannabis? This presentation synthesizes the knowns, unknowns, and practical considerations to help you provide the best guidance for your patients.

4:45 pm - 5:25 pm - Cannabis and Psychiatry: Pros and Cons throughout Human Development: Ethan Russo
This presentation will examine cognitive impairment related to cannabis, and benefits and liabilities related to depression, anxiety, and psychosis.

5:25 pm - 6:00 pm - Pharmacokinetics and Product Formulation: Understanding Cannabinoid Delivery and Extraction Methods Dustin Sulak & Bonni Goldstein
This presentation will review the pharmacokinetics of major cannabinoids—absorption, distribution, metabolism, and elimination—across various delivery systems. Clinicians will gain insight into how extraction techniques, carrier oils, and formulation technologies such as nanoemulsions and liposomal delivery influence onset, potency, and duration of effect. Practical considerations for product selection, dosing, and patient education will also be discussed to support evidence-based therapeutic use.

6:00 pm - 6:30 pm - Q&A : All Faculty